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4min chapter
iwAL 2022 Session V: mechanisms of resistance to targeted therapies in AML
VJHemOnc Podcast
Mechanisms of Resistance in IDH and Flit3 Mutant AML
This chapter explores the resistance mechanisms to targeted therapies in IDH and Flit3 mutant AML, discussing the impact of small clones, non-cell intrinsic effects, and the role of 2Hg. It also highlights the low response rates in treating relapse wild type Flit3 and the need for further understanding.
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