5min chapter

The Intern At Work: Internal Medicine cover image

117. The World’s Most Common Infection: An Approach to H Pylori Infection

The Intern At Work: Internal Medicine

CHAPTER

Introduction

H pilore is a gram negative bacterium that fects human hosts. Almost all humans who carry h pelora are infected in the first year of life, and it is unusual for adults to acquire infection later in life. The environment, host diet and genetics and the particular strain of h pilori can all influence disease expression. With chronic infections, hes factors cause breakdown and increased permability of gastric mucus and underlying epithelium. Certain strains of H pilori secrete virulence factors such as c a, g a and va c a which have also been linked to higher risk of pre malignant gastrial lesions. To day's episode is titled the world's most

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