Jay Gargus, “Autism: A Genetic Perspective” (Open Agenda, 2021)
New Books in Neuroscience
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Muto Genesis
The way we understand conventional mutations is really pretty simple. It's that instead of having the three base pairs that are normally there, you change one of the letters, and you now spell a new amino acid. And that puts a different structure of the chemistry of the protein that then makes the protein fold abnormally. The class of diseases that are much trickier to understand, and that are really important in the naropsychi atric diseases are dominant diseases. That's where the person has one perfectly good copy of the g, but one mutant copy of theG.
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