Cell Biology of Aging, Mitochondria, Metabolism, Autophagy & Stress | Andrew Dillin | 155
Mind & Matter
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Exploring the Science of Aging and Longevity
This chapter delves into the speaker's journey in cell biology, from studying ER stress to uncovering genes that profoundly affect aging like DAF in nematodes. It further explores experiments in various organisms that manipulate mitochondrial genes and aging pathways to significantly extend lifespan. The discussion also touches on the distinction between lengthening lifespan versus reversing aging, skepticism towards the latter, and the role of Abata plaques and oligomers in diseases like Alzheimer's.
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