The Effective Statistician - in association with PSI cover image

Estimands in Observational Studies

The Effective Statistician - in association with PSI

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Understanding the Estimant Framework in Observational Studies and Clinical Trials

This chapter explores the Estimant framework in relation to observational studies and clinical trials, emphasizing the differences in factors such as intact events, treatment variation, and intercurrent events. The speakers also discuss the future of real-world data research, stakeholder considerations, and the importance of rigorous sensitivity analysis.

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