Endometriosis Pathophysiology and Progression

My guest is Dr. Thaïs Aliabadi, MD, board-certified OB/GYN, surgeon and leading expert in women's health. We discuss polycystic ovary syndrome (PCOS) and endometriosis, two very common yet frequently undiagnosed causes of female infertility. Dr. Aliabadi explains the symptoms, underlying causes and evidence-based treatments for both conditions, including supplement and lifestyle interventions. We also discuss breast cancer risk and screening, pregnancy, perimenopause and menopause, and the hormone tests that women should request. This conversation offers empowering, potentially life-changing information for women of all ages to take control of their hormone, reproductive and overall health.

Read the episode show notes at hubermanlab.com.

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Timestamps

00:00 Thaïs Aliabadi

02:56 Why Endometriosis & Polycystic Ovary Syndrome (PCOS) Go Undiagnosed

08:16 Infertility, Tool: Early Screening

10:54 Sponsors: Lingo & Our Place

14:07 Women's Health Education Gap

15:24 PCOS Overview: Symptoms, Diagnosis, AMH, Disordered Eating

21:28 Irregular Periods, Teenage PCOS Diagnosis

24:36 Diagnosis, Pelvic Ultrasound; PCOS Naming

27:49 Thinning Hair & Acne; 4 PCOS Phenotypes; Mood & Treatment

35:54 Underlying Pillars of PCOS; HPA Axis, Androgens, Menstruation & Ovulation

40:30 Insulin Resistance & PCOS, Visceral Fat & Inflammation

46:30 Sponsors: AGZ by AG1 & Joovv

49:10 PCOS, Chronic Inflammation, Genetics & Lifestyle; Mood

52:31 PCOS, Fertility, Freezing Eggs, Tool: Egg Count & AMH Range By Age

58:34 Women's Health Education, AI, Clinicians; Cataracts Analogy

1:01:20 Stress; PCOS Treatment, Birth Control, Insulin Resistance & Metformin

1:06:44 PCOS Risk Calculator, Supplements, Lifestyle Factors; GLP-1s

1:12:32 Berberine, Metformin; GLP-1s, Food Anxiety & Alcohol

1:19:13 PCOS Prescriptions & Fertility; PCOS Co-Occurrence with Endometriosis

1:21:56 Sponsor: LMNT

1:23:16 PCOS Treatment, Freezing Eggs, Egg Quality; Advocate For Your Health

1:32:02 PCOS Key Takeaways: Symptoms, Tests, Supplements & Lifestyle

1:36:03 Undiagnosed Endometriosis, Fertility

1:39:26 Endometriosis: Symptoms, Diagnosis, Painful Periods, Infertility

1:42:30 Male vs Female Health Issues, Undiagnosed Endometriosis

1:47:01 Inflammation, Ectopic Implants, Chronic Pelvic Pain; Adenomyosis

1:50:36 Egg Quality, Endometriosis, Tools: Egg Counts; Pelvic Ultrasound

1:54:29 Sponsor: Function

1:56:13 Pain & Health Testing, Tool: Endometriosis Symptoms, Screening & Tests

2:01:32 Treatment, Surgery, Different Types of Endometriosis

2:05:22 Endometriosis Causes, Inflammation; Incidence, PCOS

2:11:58 Obstetrics & Gynecology Separation, Surgery

2:16:00 Endometriosis Key Takeaways: Symptoms, Treatment & Diagnosis

2:17:04 Treatment, Estrogen & Progesterone, Birth Control, GnRH Antagonists

2:22:39 Endometriosis Stage & Pain, Endometriosis Types

2:23:49 Pregnancy; Postpartum Depression, Menopause; Frustration for Patients

2:29:55 Fibroids, Surgery, Uterine Septum, Tool: Pelvic Ultrasound

2:34:05 Tool: Assessing Your & Partner's Fertility; Autoimmune Conditions

2:37:51 Breast Cancer, Tool: Lifetime Risk Calculator & Breast Imaging; Mastectomy

2:49:47 Endometriosis Tests, Autoimmune Disease; Brain Fog & Menopause; Inositol

2:53:06 Undiagnosed Infertility; PMDD Treatment; Fasting & Low-Carbohydrate Diets

2:57:21 Hair Loss & Perimenopause; Egg Quality; Endometriosis & Menopause

3:00:40 Increase Progesterone; Diet, Hormone & Menopause; Prolong Fertility

3:04:54 Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter

Disclaimer & Disclosures

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