The eteology of alsheimer disease is largely unknown, and it could be multi factorial. But i do think metabolic disregulation and a infectious agents are major contributors to not only al sheimer disease, but parkinsons and m s and al s and these things ad finally people are looking into this. And we've applied therapeuti tosis to alsheimers disease, you know. Kind of thought it was academic suicide, but went down that road nyway, because i knew thi, you know, we were on to something.