Freely Filtered 055: STOP ACE!
Freely Filtered, a NephJC Podcast
Observational Studies in Advanced CKD
The observational study is much larger, giving it much greater power to look at all of these events in more granular detail. In terms of the kidney outcomes and the mortality in cardiovascular outcomes, I think that if you just extrapolated the Stop-Ace trial to a much larger trial and ran it for a longer period of time, actually they would look really, really similar. And again, Ed Fus's study, yesterday from Jason showed that mortality and cardiovascular events were higher in those in whom rascinabition was stopped in advanced CKD. That fits with this, right? We saw 108 versus 88. Again, we don't have any stats, but it looks like discontin
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