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15min chapter
Matt Kaeberlein on Rapamycin Longevity Series | Lessons learned from two decades of Rapamycin research
Master One Thing - Rapamycin Longevity Series
Longevity Interventions and Research Evolution
The chapter explores various longevity interventions like caloric restriction, rapamycin, and potential carbos intervention with a focus on their effects in mice. It delves into the comparison between mouse and human data on metformin and NAD precursors, discussing the uncertainties around their efficacy. Additionally, it discusses the importance of studying combinations of interventions, introduces the Wernbot technology, and reflects on the evolution of aging biology research towards a more mechanistic approach.
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Discover
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Listen to the best highlights from the podcasts you love and dive into the full episode