2min chapter

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A controversial dam in the Amazon unites Indigenous people and scientists, and transplanting mitochondria to treat rare diseases

Science Magazine Podcast

CHAPTER

How Many Mitochondrials Do We Need?

In this protocol, we followed up to three years and we saw the effects usually happening within a few months. What we did saw pretty consistently was an increase in the number of normal mitochondria per cell. So there was increasing the copy numbers of the intact mitochondria in each patient per cell that wasn't encouraging. But I cannot claim that this means that this is better health necessarily.

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