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I Feel Nerdy Podcast Episode 12 - I Feel Nerdy
The ambition trial was published in the New England Journal of Medicine in March of 2022. It looked at single dose liposomal amphotericin followed by flu cytosine and fluconazole for patients with kryptococcus meningitis. What they found again negative predictive value awesome greater than 99% if these are negative you probably don't have an IFI but they actually found there were no true positives only false positives so their conclusion is that these assays should not be used. The WHO updating the kryptococcal meningitis guidelines in April of 22 so absolutely practice changing data.