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#133 – Manolis Kellis: Biology of Disease
Lex Fridman Podcast
CRISPR Targeting
You can use the CRISPR targeting system to bring in not vandalism and cutting, but you can couple it with Dead Cas9. You can basically turn on or turn off that enhancer and then see what is the impact on that gene. So these are the four ways of linking the locus to the target gene. Step number five is find the target gene; step number six is what the heck does that gene do? It's the design different cutting technologies.
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