AI identifies gene interactions to speed up search for treatment targets
Nature Podcast
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The Paradox of Glucocorticoids and IBD
This is something that the researchers are trying to figure out. And what maybe seems to be the case but sort of TBC I guess is that it's about timing. So when someone's treated with glucocorticoids that's quite a short lived treatment and in a short time it seems like these molecules might have an anti-inflammatory effect. When it comes to things like stress and this kind of chronic levels of stress that are sometimes associated with IBD this longer time frame seems to flip things on its head and turn this into a pro-inflammatory situation. But as he says this is currently in mice and there's lots to understand.
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