Folate, Valproate, and Lamotrigine
The Carlat Psychiatry Podcast
00:00
Genetic Interactions in Bipolar Treatment
This chapter explores the impact of folic acid supplementation on the effectiveness of lamotrigine in treating bipolar depression, revealing unexpected negation of benefits in some patients. It highlights the influence of the COMT gene on treatment outcomes and discusses related considerations for psychiatric medications and pregnancy.
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