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SGEM#469: You Take My Breath Away – D-dimer for Ruling out PE in High-Risk Patients

The Skeptics Guide to Emergency Medicine

CHAPTER

Evaluating D-Dimer Testing for PE

This chapter critically analyzes the reliability of D-dimer tests in ruling out pulmonary embolism (PE) in high-risk patients, particularly questioning the applicability of European studies to North American populations. It reveals significant findings from recent research, including a zero failure rate in certain tested cohorts, while emphasizing the need for larger confirmatory studies due to demographic variations.

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