Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
Book • 2020
This research paper presents a 3.
5-angstrom-resolution cryo-electron microscopy structure of the 2019-nCoV spike glycoprotein in its prefusion conformation.
The study highlights the protein's structure and its implications for understanding how the virus binds to host cells, which is crucial for developing vaccines and therapeutic antibodies.
The findings also show that the 2019-nCoV spike protein binds more tightly to the ACE2 receptor than the SARS-CoV spike protein.
5-angstrom-resolution cryo-electron microscopy structure of the 2019-nCoV spike glycoprotein in its prefusion conformation.
The study highlights the protein's structure and its implications for understanding how the virus binds to host cells, which is crucial for developing vaccines and therapeutic antibodies.
The findings also show that the 2019-nCoV spike protein binds more tightly to the ACE2 receptor than the SARS-CoV spike protein.
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Discussed by Lauren Richardson and Judy Savitskaya , focusing on its cryo-EM structure analysis of the 2019-nCoV spike protein.
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